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Primary cilia in hard tissue development and diseases

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 657-678 doi: 10.1007/s11684-021-0829-6

Abstract: Bone and teeth are hard tissues.Mutations in cilium-related genes result in a variety of developmental and even lethal diseases.Furthermore, primary cilia act as sensors of external stimuli and regulate bone homeostasis.In this review, we summarize the roles of primary cilia in long bone development and remodeling fromIn addition, the cilium-related diseases of hard tissue and the manifestations of mutant cilia in the

Keywords： primary cilia     bone     mechanical sensing     hard tissue     cilium-related bone disease     tooth    

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Identification of differentially expressed miRNAs associated with chronic kidney disease–mineral bone

Kyung Im Kim, Sohyun Jeong, Nayoung Han, Jung Mi Oh, Kook-Hwan Oh, In-Wha Kim

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 378-385 doi: 10.1007/s11684-017-0541-8

Abstract: of this study is to characterize a meta-signature of differentially expressed mRNA in chronic kidney disease(CKD) to predict putative microRNA (miRNA) in CKD–mineral bone disorder (CKD–MBD) and confirmPubMed searches using MeSH terms and keywords related to CKD, uremia, and mRNA arrays were conducted.

Keywords： chronic kidney disease     microRNA     mineral bone disorder     uremia    

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FGF13 suppresses acute myeloid leukemia by regulating bone marrow niches

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 896-908 doi: 10.1007/s11684-022-0944-z

Abstract: definite role in the development of acute myeloid leukemia (AML) and emphasize its associations with boneResults showed that FGF13 was lowly expressed in patients with AML and that its elevated expression was relatedto bone marrow niches.Overall, FGF13 could serve as an independent prognostic factor for AML, and it was closely related tothe bone marrow microenvironment.

Keywords： acute myeloid leukemia     FGF13     prognosis     immune-related genes     bone marrow niches    

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FGF23 associated bone diseases

Eryuan Liao

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 65-80 doi: 10.1007/s11684-013-0254-6

Abstract: summarized the FGF superfamily, the mechanism of FGF23 on phosphate and vitamin D metabolism, and the FGF23 relatedbone disease.

Keywords： fibroblast growth factor 23     FGF receptor     phosphate metabolism     Klotho     bone disease    

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Potential functions of esophageal cancer-related gene-4 in the cardiovascular system

Rui Zhou, Yuanshu Liu, Wenjun Huang, Xitong Dang

Frontiers of Medicine 2019, Volume 13, Issue 6,   Pages 639-645 doi: 10.1007/s11684-019-0701-0

Abstract: Esophageal cancer-related gene-4 ( ) is cloned from the normal epithelium of the esophagus.

Keywords： tumor suppressor gene     esophageal cancer-related gene-4     cardiovascular disease     hypoxia    

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Effect of laparoscopic fundoplication treatment on gastroesophageal reflux disease-related respiratory

Zhong-Gao WANG MD, FACS, Feng JI MD, PhD, Yun-Gang LAI MD, PhD, Xiang GAO MD, PhD, Cheng-Chao ZHANG MD, PhD, Ji-Min WU MD, PhD, Xiu CHEN MD, PhD, Ibrahim M. IBRAHIM MD, FACS,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 254-258 doi: 10.1007/s11684-010-0029-2

Abstract: Gastroesophageal reflux disease (GERD) was diagnosed and fundoplication was performed, which relievedThis paper explores the effect of fundoplication on GERD-related respiratory symptoms.From January 2007 to October 2008, 64 patients with respiratory symptoms related to GERD were consecutivelyLaparoscopic fundoplication can be an effective treatment for the majority of patients with GERD-related

Keywords： gastroesophageal reflux disease     pH monitoring     laparoscopic fundoplication     respiratory symptom    

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Current advances for bone regeneration based on tissue engineering strategies

Rui Shi, Yuelong Huang, Chi Ma, Chengai Wu, Wei Tian

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 160-188 doi: 10.1007/s11684-018-0629-9

Abstract: Bone tissue engineering (BTE) is a rapidly developing strategy for repairing critical-sized bone defectsto address the unmet need for bone augmentation and skeletal repair.Effective therapies for bone regeneration primarily require the coordinated combination of innovativeHowever, current techniques in bone tissue engineering have not yet reached valid translation into clinicalovercome these shortcomings and facilitate the clinical application of these techniques to enhance bone

Keywords： bone tissue engineering     stem cell     bone scaffold     growth factor     bone regeneration    

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Mesenchymal Stem Cells Represent a Therapeutic Option for Coronavirus Disease 2019-Related Acute Respiratory

Xuan Zhao, Yi Zhang

Engineering 2020, Volume 6, Issue 10,   Pages 1073-1075 doi: 10.1016/j.eng.2020.05.015

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Autologous bone marrow stem cell transplantation for the treatment of ulcerative colitis complicated

Hang Xiang,Xiaomei Zhang,Chao Yang,Wenhuan Xu,Xin Ge,Rong Zhang,Ya Qiu,Wanjun Sun,Fan Li,Tianyuan Xiang,Haixu Chen,Zheng Wang,Qiang Zeng

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 522-526 doi: 10.1007/s11684-016-0485-4

Abstract:

Ulcerative colitis (UC) is a chronic inflammatory bowel disease with continuous or recurrent symptomsTherefore, we performed an autologous bone marrow cells to modulate the immune system with his permissionAutologous bone marrow mononuclear cells were collected and injected locally into the bowel mucosa, andAfter the patient underwent auto bone marrow mononuclear cells transplantations twice, the patient&rsquo

Keywords： autograft     bone marrow stem cells     ulcerative colitis     cell therapy    

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Machinability of ultrasonic vibration-assisted micro-grinding in biological bone using nanolubricant

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 1, doi: 10.1007/s11465-022-0717-z

Abstract: Bone grinding is an essential and vital procedure in most surgical operations.results showed that U-NJMC provides a novel approach for clinical surgical micro-grinding of biological bone

Keywords： micro-grinding     biological bone     ultrasonic vibration (UV)     nanoparticle jet mist cooling (NJMC)     grinding    

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Hybrid polymer biomaterials for bone tissue regeneration

Bo Lei, Baolin Guo, Kunal J. Rambhia, Peter X. Ma

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 189-201 doi: 10.1007/s11684-018-0664-6

Abstract: The review further exemplifies their applications for bone tissue regeneration.

Keywords： hybrid polymer     bone regeneration     tissue engineering     biomaterials    

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Influence of Probiotic Fermented Fruit and Vegetables on Human Health and the Related Industrial Development Review

Qianqian Guan, Tao Xiong, Mingyong Xie

Engineering 2021, Volume 7, Issue 2,   Pages 212-218 doi: 10.1016/j.eng.2020.03.018

Abstract: vegetables, and discusses the main achievements of our group in this field and future developments of the related

Keywords： Probiotic     Fermented fruit and vegetables     Human health     Chronic disease prevention    

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Progress of three-dimensional macroporous bioactive glass for bone regeneration

Lijun JI, Yunfeng SI, Ailing LI, Wenjun WANG, Dong QIU, Aiping ZHU

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 4,   Pages 470-483 doi: 10.1007/s11705-012-1217-1

Abstract: excellent osteoconductive, osteoinductive, biocompatible and biodegradable properties, and their high boneMacroporous scaffolds made from BGs are in high demand for bone regeneration because they can stimulatevascularized bone ingrowth and they enhance bonding between scaffolds and surrounding tissues.progress in the past few years in preparing three-dimensional macroporous BG and BG/BP scaffolds for bone

Keywords： bioactive glass     biopolymer     bone regeneration     macroporous scaffolds     tissue engineering    

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Thermochemical pretreatment of meat and bone meal and its effect on methane production

Guangxue WU , Zhenhu HU , Mark G. HEALY , Xinmin ZHAN ,

Frontiers of Environmental Science & Engineering 2009, Volume 3, Issue 3,   Pages 300-306 doi: 10.1007/s11783-009-0031-6

Abstract: Since the solubilization of meat and bone meal (MBM) is a prerequisite in many MBM disposal approaches

Keywords： thermochemical pretreatment     meat and bone meal     solid reduction     solid solubilization     methane production    

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Bone metastasis of hepatocellular carcinoma: facts and hopes from clinical and translational perspectives

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 551-573 doi: 10.1007/s11684-022-0928-z

Abstract: Patients with hepatocellular carcinoma (HCC) and bone metastasis (BM) suffer from greatly reduced lifediagnosis, prognosis, and therapeutic approaches of HCC BM are detailed to provide a panoramic view of this diseaseWe further delineate an informative cancer bone metastatic cascade based on evidence from recent studiesand point out the main factors responsible for the tumor-associated disruption of bone homeostasis and

Keywords： HCC     bone     osteotropism     clinical     basic researches     advances    

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Title Author Date Type Operation

Primary cilia in hard tissue development and diseases

Journal Article

Identification of differentially expressed miRNAs associated with chronic kidney disease–mineral bone

Kyung Im Kim, Sohyun Jeong, Nayoung Han, Jung Mi Oh, Kook-Hwan Oh, In-Wha Kim

Journal Article

FGF13 suppresses acute myeloid leukemia by regulating bone marrow niches

Journal Article

FGF23 associated bone diseases

Eryuan Liao

Journal Article

Potential functions of esophageal cancer-related gene-4 in the cardiovascular system

Rui Zhou, Yuanshu Liu, Wenjun Huang, Xitong Dang

Journal Article

Effect of laparoscopic fundoplication treatment on gastroesophageal reflux disease-related respiratory

Zhong-Gao WANG MD, FACS, Feng JI MD, PhD, Yun-Gang LAI MD, PhD, Xiang GAO MD, PhD, Cheng-Chao ZHANG MD, PhD, Ji-Min WU MD, PhD, Xiu CHEN MD, PhD, Ibrahim M. IBRAHIM MD, FACS,

Journal Article

Current advances for bone regeneration based on tissue engineering strategies

Rui Shi, Yuelong Huang, Chi Ma, Chengai Wu, Wei Tian

Journal Article

Mesenchymal Stem Cells Represent a Therapeutic Option for Coronavirus Disease 2019-Related Acute Respiratory

Xuan Zhao, Yi Zhang

Journal Article

Autologous bone marrow stem cell transplantation for the treatment of ulcerative colitis complicated

Hang Xiang,Xiaomei Zhang,Chao Yang,Wenhuan Xu,Xin Ge,Rong Zhang,Ya Qiu,Wanjun Sun,Fan Li,Tianyuan Xiang,Haixu Chen,Zheng Wang,Qiang Zeng

Journal Article

Machinability of ultrasonic vibration-assisted micro-grinding in biological bone using nanolubricant

Journal Article

Hybrid polymer biomaterials for bone tissue regeneration

Bo Lei, Baolin Guo, Kunal J. Rambhia, Peter X. Ma

Journal Article

Influence of Probiotic Fermented Fruit and Vegetables on Human Health and the Related Industrial Development

Qianqian Guan, Tao Xiong, Mingyong Xie

Journal Article

Progress of three-dimensional macroporous bioactive glass for bone regeneration

Lijun JI, Yunfeng SI, Ailing LI, Wenjun WANG, Dong QIU, Aiping ZHU

Journal Article

Thermochemical pretreatment of meat and bone meal and its effect on methane production

Guangxue WU , Zhenhu HU , Mark G. HEALY , Xinmin ZHAN ,

Journal Article

Bone metastasis of hepatocellular carcinoma: facts and hopes from clinical and translational perspectives

Journal Article